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PDRN Therapy (Skin Boosters)

What is it?

PDRN Therapy is an advanced regenerative skin treatment that uses polynucleotides (PDRN) derived from purified salmon DNA to repair, rejuvenate, and deeply hydrate the skin at a cellular level. Known for its powerful healing, anti-inflammatory, and collagen-stimulating properties, PDRN restores skin health from within. It improves elasticity, refines texture, reduces pigmentation, and enhances overall radiance, making it ideal for dull, damaged, sensitive, or prematurely ageing skin. PDRN skin boosters offer subtle, natural-looking rejuvenation without altering facial contours.

Uses of PDRN Therapy

PDRN is highly effective for:

  • Dull, dehydrated, or tired-looking skin
  • Fine lines and early ageing
  • Pigmentation and uneven skin tone
  • Acne scars and textural irregularities
  • Under-eye hollowness and dark circles
  • Sensitive or damaged skin
  • Crepey skin on the neck, chest, and hands
  • Post-inflammatory healing and skin repair
How PDRN Works

PDRN contains bioactive DNA fragments that mimic the body’s natural repair signals. Once delivered into the skin, it:

  • Stimulates fibroblasts to boost collagen and elastin
  • Improves microcirculation, enhancing oxygen and nutrient delivery
  • Reduces inflammation, calming sensitive or compromised skin
  • Accelerates tissue repair and cellular regeneration
  • Enhances hydration by strengthening the skin’s moisture-retention capacity

This allows PDRN to repair skin from within, not just improve surface appearance.

Indications

Eyes

  • Under-eye hollowness
  • Dark circles
  • Fine lines and wrinkles
  • Upper eyelid crepiness and pigmentation
  • Preventive care to delay the need for fillers

Face

  • Overall glow and injectable hydration
  • Facial pigmentation and uneven tone
  • Post-inflammatory hyperpigmentation (PIH)
  • Acne scars and enlarged pores
  • Skin quality improvement and rejuvenation
  • LPP (Lichen Planus Pigmentosus)
  • PDL (Pigmentary Demarcation Lines)
  • Sensitive skin requiring cellular balance
  • Wound healing and post-procedure recovery

Neck

  • Neck bands
  • Crepey or thinning neck skin
  • Sagging neck

Hands

  • Pigmentation of hands
  • Dehydration and crepey skin
  • Overall skin rejuvenation
Procedure Overview

PDRN boosters are delivered through microinjections into the superficial to mid-dermis using:

  • Manual Mesotherapy – point-by-point or microdroplet technique
  • Injection devices – microneedling or injector pens

The method used depends on skin needs and treatment goals.

The treatment is usually performed under topical anaesthesia to minimise discomfort. A full-face session takes approximately 20–30 minutes, depending on the technique used and the treatment area.

Post-procedure, patients may experience mild redness, pinpoint bruising, or swelling, which generally resolves within 1–3 days.

What to Expect Before & After PDRN Therapy

Before the treatment:

  • A detailed consultation determines suitability and treatment areas
  • Numbing cream is applied prior to injections
  • Avoid active skincare if advised

After the treatment:

  • Mild redness or swelling may appear and settles within 24–48 hours
  • Skin appears more hydrated and refreshed within a few days
  • Collagen stimulation continues over several weeks
  • A series of sessions is recommended for optimal results
Treatment Protocol & Improvement

Standard Protocol

  • 3–4 sessions spaced 3–4 weeks apart
  • Maintenance sessions every 4–6 months, depending on skin goals

Expected Improvement

  • Enhanced hydration and glow
  • Smoother texture and refined pores
  • Improved elasticity and firmness
  • Reduction in pigmentation and fine lines

Stronger, healthier skin over time

Important Notes

Skin Sensitivity:

  • Mild swelling or redness may occur temporarily. This treatment is generally safe for all skin types, including sensitive skin.

Post-Treatment Care:

  • Avoid active skincare (retinoids, exfoliants) for 48 hours.
  • Do not expose skin to direct sunlight for 3–5 days; use SPF diligently.
  • Avoid alcohol, sauna, and intense exercise for 24 hours.

Consultation:

  • Individuals who are pregnant, breastfeeding, or have active infections should consult with a dermatologist before proceeding.
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